|
Thomas Killian’s research group studies ultracold neutral plasmas and quantum degenerate atomic atomic
gases. Both experiments start with laser-cooled and trapped neutral strontium. Laser-cooling is a powerful
technique for producing and trapping atoms at temperatures as low as one millionth of a degree above
absolute zero. Under these exotic conditions, matter behaves in fundamentally different ways, and the
exploration of this regime teaches us about the basic laws of nature and lays the foundation for powerful
new technological advances.
Several of our current projects focus on creating and understanding strongly interacting, many-body systems. This is a grand challenge for many areas of physics because such systems often display rich emergent phenomena and phases that are beyond the reach of current theoretical and numerical tools to describe.
Ultracold neutral plasmas are strongly interacting because their
thermal energy is less than the Coulomb energy between neighboring particles, which reverses the normal
energy hierarchy found in plasmas. Strong coupling is also found in dense astrophysical plasmas and high-energy plasma created through intense laser-matter interaction, and our experiments serve as simulators that can benchmark theories of these more complex systems.
In the quantum realm, the highly
entangled wavefunctions in strongly interacting systems lead to the emergence of new physics, such as high-temperature superconductivity.
Ultracold atoms can reach this regime when they are trapped in periodic potentials called optical lattices. We are currently developing new techniques to probe strontium gases in optical lattices and detect spatial correlations and phase transitions that arise in strongly interacting systems.
Highly excited Rydberg atoms display strong interactions with other atoms and with their environment due to their extreme polarizability (sensitivity to electric fields). We are using the properites of Rydberg atoms to create a new type of quantum simulator that will allow us to simulate toplogical states of matter.
A Rydberg atom embedded in a dense, ultracold gas, such as a Bose-Einstein condensate (BEC), can also form a bizare type of molecule called an 'ultra-long-range Rydberg molecule', in which background atoms are bound to the Rydberg core by weak interactions with the Rydberg electron. These molecules can be as large as a grain of sand, and they provide a fruitful playground for studying few-body quantum systems. Experiments in our laboratory have focused on molecular lifetimes and the perturbation of a BEC when an impurity Rydberg atom is created inside it.
Ultracold Neutral Plasmas
Over 99% of the visible matter in the universe exists as plasma, in which neutral atoms have been
ionized to produce free electrons and ions. Traditionally, neutral plasmas are relatively hot, such as the
solar corona (1,000,000 K), a candle flame (1000 K), or the ionosphere around our planet (300 K). Using
techniques of laser cooling, which originated in the atomic physics community, it is now possible to create
ultracold neutral plasmas at temperatures as low as about 50 mK. In a table-top apparatus, laser light traps
and cools about 1 billion neutral atoms to a thousandth of a degree above absolute zero. A second laser
illuminates the cloud with photons with barely enough energy to ionize the atoms and create the plasma.
Plasmas in the ultracold regime are challenging to describe theoretically
because they are strongly interacting, which means that interactions cannot be treated as a small
perturbation. We have ongoing projects measuring transport and collision rates in strongly coupled systems, which provides validation for molecular dynamics simulations that are also applied to dense plasmas in thermonuclear devices and the cores of gas giant planets.
We recently demonstrated laser cooling of ions in an ultracold plasma, which is the first time anyone has successfully laser-cooled a neutral plasma. This gives access to colder and more strongly coupled systems. More work is needed to understand the limits of laser cooling in this setting.
We have also developed techniques for sculpting the density distribution of the plasma, which
allows us to excite ion acoustic waves and create streaming plasmas and shock waves. This represents a new
direction in the study of ultracold neutral plasmas that will allow us to probe basic plasma physics
phenomena with unprecedented precision. Another frontier we are exploring is the dynamics of ultracold plasmas in magnetic fields, and we have seen evidence for magnetic trapping of the plasma in a quadrupole field configuration.
Working with Professor Stephen Bradshaw, a solar and compuational astrohpysicist at Rice, we are using ultracold plasmas to explore phenomena of interest for solar and near-Earth plasmas, such as wave phenomena in the solar corona and the interaction of the solar wind with the Earth's magnetic field.
Publications
|
"Laser-Induced-Fluorescence Imaging of a Spin-Polarized Ultracold Neutral Plasma in a Magnetic Field,"
G. M. Gorman, M. K. Warrens, S. J. Bradshaw, and T. C. Killian Phys. Rev. A. 105, 013108 (2022).
|
|
"Expansion of Ultracold Neutral Plasmas with Exponentially Decaying Density Distributions,"
MacKenzie K. Warrens, Grant M. Gorman, Stephen J. Bradshaw, Thomas C. Killian,Phys. Plasmas 28, 022110 (2021).
|
|
|
"Magnetic Confinement of an Ultracold Neutral Plasma," G. M. Gorman, M. K. Warrens, S. J. Bradshaw, and T. C. Killian
Phys. Rev. Lett. 126, 085002 (2021).
|
|
|
"Combined Molecular Dynamics and Quantum Trajectories Simulation of Laser-driven,
Collisional Systems," G.M. Gorman, T.K. Langin, M.K. Warrens, D. Vrinceanu, T.C. Killian, Phys. Rev. A 101, 012710 (2020).
|
|
"Exploring the Crossover Between High-energy-density Plasma and Ultracold
Neutral Plasma Physics," S. D. Bergeson, Scott D. Baalrud, C. Leland Ellison, Ed Grant, Frank R. Graziani, T. C.
Killian, M. S. Murillo, Jacob Roberts, and L. G. Stanton,
Phys. Plasmas 26, 100501 (2019).
|
|
"Laser Cooling of Ions in a Neutral Plasma," T.K. Langin, G.M. Gorman, and T.C. Killian,
Science 363, 61 (2019).
|
|
"Experimental Measurement of Self-Diffusion in a Strongly Coupled Plasma," T.S. Strickler, T.K. Langin, P. McQuillen, J. Daligault, and T.C. Killian,
Phys. Rev X 6, 021021 (2016).
|
|
"Demonstrating universal scaling
for dynamics of Yukawa one-component plasmas after an interaction quench," T.K Langin, T.Strickler, N.
Maksimovic, P. McQuillen, T. Pohl, D. Vrinceanu, and T. C. Killian, Phys. Rev. E.
93, 023201 (2016).
|
|
|
"Ion Temperature Evolution in an Ultracold Neutral Plasma," P. McQuillen, T. Strickler, T. Langin, and T. C. Killian, Phys. Plasmas
22, 033513 (2015).
|
|
"Emergence of Kinetic Behavior in Streaming Ultracold Neutral Plasmas," P. McQuillen, J. Castro, S. J. Bradshaw, and T. C. Killian, Phys. Plasmas
22, 043514 (2015).
|
|
"Strongly Coupled Plasmas via
Rydberg-Blockade of Cold Atoms," G. Bannasch, T. C. Killian, and T. Pohl, Phys. Rev. Lett.
110, 253003 (2013).
|
|
"Ion Holes in the
Hydrodynamic Regime in Ultracold Neutral Plasmas," P. McQuillen, J. Castro, T. Strickler, S.
J. Bradshaw, and T. C. Killian, Phys. Plasmas
20, 043516 (2013).
|
|
"Imaging the Evolution of an
Ultracold Strontium Rydberg Gas," P. McQuillen, X. Zhang, T. Strickler, F. B. Dunning, and
T. C. Killian, Phys. Rev. A.
87, 013407 (2013).
|
|
"Velocity Relaxation in a
Strongly Coupled Plasma," G. Bannasch, J. Castro, P. McQuillen, T. Pohl, and T. C. Killian,
Phys. Rev. Lett.
109, 185008 (2012).
|
|
"Creating and Studying Ion
Acoustic Waves in Ultracold Neutral Plasmas," T. C. Killian, P. McQuillen, T. O'Neil and
J. Castro, Phys. Plasmas
19, 055701 (2012).
|
|
"Creating Non-Maxwellian
Velocity Distributions in Ultracold Plasmas," J. Castro, G. Bannasch, P. McQuillen, T. Pohl
and T. C. Killian, AIP Conf. Proc.
1421, 31 (2011).
|
|
"High-Resolution
Ionization of Ultracold Neutral Plasmas," P. McQuillen, J. Castro, and T.C. Killian, J.
Phys. B.
44, 184013 (2011).
|
|
"Ion Acoustic Waves in Ultracold
Neutral Plasmas," J. Castro, P. McQuillen, and T.C. Killian, Phys. Rev. Lett.
105, 065004 (2010).
|
|
"Ultracold Neutral Plasmas," T.C. Killian and S. L Rolston, Phys. Today
63, 46 (2010).
|
|
"Using Sheet Fluorescence to
Probe Ion Dynamics in Ultracold Neutral Plasmas." J. Castro, H. Gao, and T. C. Killian,
Plasma Phys. Control. Fusion
50, 124011 (2008).
|
|
"Optical Probes of Ultracold Neutral Plasmas," S. Laha, J. Castro, H. Gao, P. Gupta,
C.E. Simien, and T. C. Killian, AIP Conf. Proc.
926, 69 (2007).
|
|
"Ultracold
Neutral Plasmas", T. C. Killian, T. Pattard, Thomas Pohl, and J. M. Rost, Phys. Rep.
449, 77 (2007).
|
|
"Ultracold Neutral Plasmas", Thomas C. Killian, Science
316, 705 (2007).
|
|
"Optical Probes of Ultracold Neutral Plasmas," CP926, Atomic Processes in
Plasmas--15th International Conference on Atomic Process in Plasmas, edited by J.D. Gillaspy,
J.J. Curry, and W.L. Wiese (2007).
|
|
"Experimental Realization of
an Exact Solution to the Vlasov Equations for an Expanding Plasma," S. Laha, P. Gupta, C.E.
Simien, H. Gao, J. Castro, T. Pohl, and T. C. Killian, Phys. Rev. Lett. 99, 155001 (2007).
|
|
"Electron Temperature
Evolution in Expanding Ultracold Neutral Plasmas," P. Gupta, S. Laha, C.E. Simien, H. Gao,
J. Castro, T. C. Killian, and T. Pohl, Phys. Rev. Lett. 99, 075005 (2007).
|
|
"Kinetic Energy
Oscillations in Annular Regions of Ultracold Neutral Plasmas," S. Laha, Y. C. Chen, P.
Gupta, C.E. Simien, Y.N. Martinez, P.G. Mickelson, S.B. Nagel, and T.C. Killian, Eur. Phys. J. D
40, 51 (2006).
|
|
"Absorption Imaging and
Spectroscopy of Ultracold Neutral Plasmas," T. C. Killian, Y. C. Chen, P. Gupta, S. Laha, Y.
N. Martinez, P. G. Mickelson, S. B. Nagel , A. D. Saenz, and C. E. Simien, J. Phys. B, 38, 351
(2005).
|
|
Electron Screening and Kinetic
Energy Oscillations in a Strongly Coupled Plasma," Y.C. Chen, C.E. Simien, P. Gupta, S.
Laha, Y.N. Martinez, P.G. Mickelson, S.B. Nagel, and T.C. Killian, Phys. Rev. Lett. 93, 265003
(2004).
|
|
"Using Absorption Imaging to
Study Iron Dynamics in an Ultracold Neutral Plasma," C. E. Simien, Y. C. Chen, P. Gupta, S.
Laha, Y. N. Martinez, P. G. Mickelson, S. B. Nagel, and T. C. Killian, Phys. Rev. Lett. 92,
143001 (2004).
|
|
"Plasmas Put in
Order," T.C. Killian, Nature 429, 815 (2004).
|
Theses
Quantum Degenerate Atomic Strontium: Rydberg Atoms, Lattices, and More
Our work on ultracold neutral atomic strontium focuses on the study of quantum degenerate gases. When
atoms are cooled down to temperatures on the order of a millionth of a degree above absolute zero, they
enter a regime dominated by quantum mechanics in which we can search for new phenomena and explore novel
states of matter, Using ultracold atoms as quantum simulators, we can probe the underlying physics of magnetism and superconductivity. Ultracold atoms serve
as ideal model systems because the individual particles are well characterized, and their interactions can
be controlled in ways that are not possible with traditional materials. Strontium in particular, has two
valence electrons, which is unlike most other elements that have been coaxed into the quantum degenerate
regime, and this has been predicted to lead to new types of collective properties at ultracold
temperatures.
In 2009 and 2010, we created the first strontium Bose-Einstein condensates and quantum
degenerate Fermi gases, and we are currently developing new ways to control the interactions between atoms
using laser light. Atoms can also be promoted to highly excited Rydberg states, which interact with each other with strong, long-range forces due to the large dipole moments possible in these states. Dipolar interactions are predicted to lead to exotic phenomena such as supersolidity and three-dimensional solitons. When Rydberg atoms are formed in relatively dense ultracold gases, such as a Bose-Einstein condensate, ground-state atoms can be trapped inside the orbital of the weakly bound Rydberg electron, forming what is known as an 'ultralong-range Rydberg molecule.' Strontium has many advantages for these experiments. We are currently exploring reactions and decay processes involving this new type of molecule, and we are using the excitation rates of ultralong-range Rydberg molecules to probe non-local spatial correlations in quantum gases. By coupling multiple Rydberg states with resonant microwave fields, we can construct a synthetic dimension of internal atomic states, and we are using these new ideas to simulate topological states of matter.
Publications
|
"Measuring nonlocal three-body spatial correlations with Rydberg trimers in ultracold quantum gases," S. K. Kanungo, Y. Lu, F. B. Dunning, S. Yoshida, J. Burgdörfer, and T. C. Killian, Phys. Rev. A 107, 033322 (2023).
|
|
"Resolving rotationally excited states of ultralong-range Rydberg molecules," Y. Lu, J. D. Whalen, S. K. Kanungo, T. C. Killian, F. B. Dunning, S. Yoshida, and J. Burgdörfer, Phys. Rev. A 106, 022809 (2022).
|
|
"Realizing topological edge states with Rydberg-atom synthetic dimensions," S. K. Kanungo, J. D. Whalen, Y. Lu, M. Yuan, S. Dasgupta, F. B. Dunning, K. R. A. Hazzard, and T. C. Killian, Nature Communications 13, 972 (2022).
|
|
"Photoassociative Spectroscopy of 87-Sr," J. C. Hill, W. Huie, P. Lunia, J. D. Whalen, S. K. Kanungo, Y. Lu, and T. C. Killian, Phys. Rev. A 103, 023111 (2021).
|
|
"Loss rates for high-n, 49 ≤n≤ 150, 5sns(3s1) Rydberg atoms excited in an 84-Sr Bose-Einstein condensate," S. K. Kanungo, J. D. Whalen, Y. Lu, T. C. Killian, F. B. Dunning, S. Yoshida, J. Burgdörfer , Phys. Rev. A 102, 063317 (2021).
|
|
"Heteronuclear Rydberg molecules," J. D. Whalen, S. K. Kanungo, Y. Lu, S. Yoshida, J. Burgdörfer, F. B. Dunning, and T. C. Killian, Phys. Rev. A 101, 060701(R) (2020).
|
|
|
"Rydberg Impurity in a Fermi Gas: Quantum Statistics and Rotational Blockade,"
John Sous, H. R. Sadeghpour, T. C. Killian, Eugene Demler, and Richard Schmidt,
Phys. Rev. Research 2, 023021 (2020).
|
|
"Creation of Vibrationally-excited Ultralong-range Rydberg Molecules in Polarized and Unpolarized Cold Gases of 87Sr,"
R. Ding, S. K. Kanungo, J. D. Whalen, T. C. Killian, F. B. Dunning, S. Yoshida, J. Burgdorfer,
J. Phys. B: At. Mol. Opt. Phys. 53, 014002 (2020).
|
|
"Formation of Ultralong-range Fermionic Rydberg Molecules in 87-Sr: Role of Quantum Statistics,"
J. D. Whalen, R. Ding, S. K. Kanungo, T. C. Killian, S. Yoshida, J. Burgdorfer
and F. B. Dunning,
Molecular Physics 117, 3088 (2019).
|
|
"Probing Nonlocal Spatial Correlations in Quantum Gases with Ultra-long-Range
Rydberg Molecules,"
J. D. Whalen, S. K. Kanungo, R. Ding, M. Wagner, R. Schmidt, H. R. Sadeghpour, S. Yoshida, J. Burgdorfer, F. B. Dunning, and T. C. Killian,
Phys. Rev. A 100, 011402(R) (2019).
|
|
"High-intensity Two-frequency Photoassociation Spectroscopy of a Weakly Bound
Molecular State: Theory and Experiment,"
W. Y. Kon, J. A. Aman, J. C. Hill, T. C. Killian, and Kaden R. A. Hazzard,
Phys. Rev. A 100, 013408 (2019).
|
|
"Photoassociative spectroscopy of a halo molecule in 86-Sr,"
J. A. Aman, J. C. Hill, R. Ding, Kaden R. A. Hazzard, T. C. Killian, and W. Y. Kon,
Phys. Rev. A 98, 053441 (2018).
|
|
|
"Spectroscopy of 87-Sr Triplet Rydberg States,"
R. Ding, J. D. Whalen, S. K. Kanungo, T. C. Killian, F. B. Dunning, S. Yoshida, and J. Burgdorfer,
Phys. Rev. A 98, 042505 (2018).
|
|
"Theory of Excitation of Rydberg Polarons in an Atomic Quantum Gas,"
R. Schmidt, J. D. Whalen, R. Ding, F. Camargo, G. Woehl Jr., S. Yoshida, and J. Burgdorfer, F. B. Dunning, H. R. Sadeghpour, E. Demler and T. C. Killian,
Phys. Rev. A 97, 022707 (2018).
|
|
"Creation of Rydberg Polarons in a Bose Gas,"
F. Camargo, R. Schmidt, J. D. Whalen, R. Ding, G. Woehl, Jr., S. Yoshida, J. Burgdörfer, F. B. Dunning, H. R. Sadeghpour, E. Demler, and T. C. Killian,
Phys. Rev. Lett. 120, 083401 (2018).
|
|
"Resonant Rydberg Dressing of Alkaline-Earth Atoms via Electromagnetically Induced Transparency,"
C. Gaul, B.J. DeSalvo, J.A. Aman, F.B. Dunning, T.C. Killian, and T. Pohl,
Phys. Rev. Lett. 116, 243001 (2016).
|
|
|
"Lifetimes of Ultra-long-range Strontium Rydberg Molecules in a Dense BEC," J. D. Whalen, F. Camargo, R. Ding, T. C. Killian, F. B. Dunning, J. Perez-Rios, S. Yoshida, and J. Burgdorfer,
Phys. Rev. A. 96, 042702 (2017).
|
|
"Accessing Rydberg-dressed Interactions Using Many-body Ramsey Dynamics," R. Mukherjee, T. C. Killian, K. R. A. Hazzard,
Phys. Rev. A. 94, 053422 (2016).
|
|
"Trap losses induced by near-resonant Rydberg dressing of cold atomic gases,"
J. A. Aman, B. J. DeSalvo, F. B. Dunning, T. C. Killian, S. Yoshida, and J. Burgdörfer,
Phys. Rev. A. 93, 043426 (2016).
|
|
"Rydberg-blockade effects in Autler-Townes spectra of ultracold strontium,"
B. J. DeSalvo, J. A. Aman, C. Gaul, T. Pohl, S. Yoshida, J. Burgdörfer, K. R. A. Hazzard, F. B. Dunning, and T. C. Killian,
Phys. Rev. A. 93, 022709 (2016).
|
|
"Ultra-long-range Rydberg molecules in a divalent atomic system,"
B. J. DeSalvo, J. A. Aman, F. B. Dunning, T. C. Killian, H. R. Sadeghpour, S. Yoshida, and J. Burgdörfer,
Phys. Rev. A. 92, 031403(R) (2015).
|
|
"Production of very-high-n strontium Rydberg atoms," S. Ye, X. Zhang, T. C. Killian, F. B. Dunning, M. Hiller, S. Yoshida, S. Nagele, J. Burgdorfer, Phys. Rev. A
88, 043430 (2013).
|
|
"Mass scaling and nonadiabatic effects in photoassociation spectroscopy of ultracold strontium atoms" Mateusz Borkowski, Piotr Morzyński, Roman Ciuryło, Paul S. Julienne, Mi Yan, Brian J. DeSalvo, and T. C. Killian,Phys. Rev. A
90, 032713 (2014).
|
|
"Rabi Oscillations between Atomic and Molecular
Condensates Driven with Coherent One-Color Photoassociation," Mi Yan, B. J. DeSalvo, Y.
Huang, P. Naidon, and T. C. Killian, Phys. Rev. Lett.
111, 150402 (2013).
|
|
|
"Degenerate Quantum Gases of Strontium," S.
Stellmer, F. Schreck, and T. C. Killian, submitted Annual Review of Cold Atoms and Molecules,
vol. 2. Ed. by K. W. Madison, Y. Wang, A. M. Rey, and K. Bongs, arxiv.org/1307.0601 (2013).
|
|
"Controlling Condensate Collapse
and Expansion with an Optical Feshbach Resonance," M. Yan, B. J. DeSalvo, B. Ramachandhran,
H. Pu, and T. C. Killian, Phys. Rev. Lett.
110, 123201 (2013).
|
|
"Numerical Modeling of Collisional
Dynamics of Sr in an Optical Dipole Trap," M. Yan, R. Chakraborty, A. Mazurenko, P. G.
Mickelson, Y. N. Martinez de Escobar, B. J. DeSalvo, and T. C. Killian , Phys. Rev. A
83, 032705 (2011).
|
|
"Degerate Fermi Gas of
87-Sr," B. J. DeSalvo, M. Yan, P. G. Mickelson, Y. N. Martinez de Escobar, and T.C. Killian,
Phys. Rev. Lett.
105, 030402 (2010).
|
|
|
"Bose-Eistein Condensation of 88-Sr
Through Sympathetic Colling with 87-Sr," P.G. Mickelson, Y. N. Martinez de Escobar, M. Yan,
B. J. DeSalvo, and T. C. Killian, Phys. Rev. A
81, 051601 (R) (2010).
|
|
"Bose-Einstein Condensation of
84-Sr," Y. N. Martinez de Escobar, P. G. Mickelson, M. Yan, B. J. DeSalvo, S. B. Nagel and T.
C. Killian, Phys. Rev. Lett.
103, 200402 (2009).
Featured in
Physics, Physics World, e! Science News, Nanotechwire, and Rice News.
|
|
|
"Repumping and Spectroscopy of
Laser-cooled Sr Atoms Using the (5s5p)3P2 - (5s4d)3D2transition," P. G. Mickelson, Y. N.
Martinez de Escobar, P. Anzel, B. J. DeSalvo, S. B. Nagel, A. J. Traverso, M. Yan, T. C. Killian,
J. Phys. B
42, 235001, (2009).
|
|
"Inelastic and Elastic Collision
Rates for Triplet States of Ultracold Strontium," A. Traverso, R. Chakraborty, Y. N.
Martinez de Escobar, P. G. Mickelson, S. B. Nagel, M. Yan, and T. C. Killian, Phys. Rev. A
79, 060702 (R) (2009).
|
|
"Two-Photon Photoassociative
Spectroscopy of Ultracold 88-Sr," Y. N. Martinez de Escobar, P. G. Mickelson, P. Pellegrini,
S. B. Nagel, A. Traverso, M. Yan, R. Cote, and T. C. Killian, Phys. Rev. A
78, 062708 (2008).
|
|
"Modification of Atom
Scattering Using an Intercombination-line Optical Feshbach Resonance at Large Detuning," Y.
N. Martinez de Escobar, P. G. Mickelson, M. Yan, and T. C. Killian, arXiv:0906.1837 (2009).
|
|
"Pumped Quantum Systems: Immersion Fluids
of the Future?" Vikas Anant, Magnus Raadmark, Ayman F. Abouraddy, Thomas C. Killian, Karl K.
Berggren, physics/0509228
|
|
"Spectroscopic Determination
of the s-Wave Scattering Lengths of 86-Sr and 88-Sr," P. G. Mickelson, Y. N. Martinez, A. D.
Saenz, S. B. Nagel, Y. C. Chen, T. C. Killian, P. Pellegrini, and R. Cote, Phys. Rev. Lett.
95, 223002 (2005).
|
|
"Photoassociatie Spectroscopy
at Long Range in Ultracold Strontium," S. B. Nagel, P. G. Mickelson, A. D. Saenz, Y. N.
Martinez, Y. C. Chen, T. C. Killian, P. Pellegrini, and R. Cote, Phys. Rev. Lett.
94, 083004 (2005).
|
|
"Magnetic
Trapping of Metastable 3P2 Atomic Strontium," S. B. Nagel, C. E. Simien, S. Laha, P. Gupta,
V. S. Ashoka, and T. C. Killian, Phys. Rev. A
67, 011401 (2003).
|
Theses
Manipulating Biological Systems with Electric and Magnetic Fields (Not Currently Active)
In collaboration with Robert Raphael in Bioengineering and Biotech startup n3D Biosciences, Inc., we developed techniques to manipulate
cells and probe cell membranes with electromagnetic fields, including levitation of cells for three-dimensional cell culturing.
Publications
|
"Magnetic Nanoparticles for 3D Cell Culture," G. R. Souza, T. C. Killian, R. M. Raphael, and H. Tseng, Nanomagnetic Actuation in Biomedicine, CRC Presss, p. 241 (2018).
|
|
"A high-throughput three-dimensional cell migration assay for toxicity screening with mobile device-based macroscopic image analysis," David M. Timm, M. S., Jianbo Chen, B. S., David Sing, B. S., Jacob A. Gage, B. S., William L. Haisler, B. S., Shane K. Neeley, B. A., Robert M. Raphael, Ph. D., Mehdi Dehghani, Ph. D., Kevin P. Rosenblatt, M. D. Ph. D., T. C. Killian, Hubert Tseng, and Glauco R. Souza, Scientific Reports
3, 3000 (2013).
|
|
"Three- dimensional
cell culturing by magnetic levitation," William L. Haisler, David M. Timm, Jacob A. Gage,
Hubert Tseng, T. C. Killian, Glauco R. Souza, Nature Protocals
8, 1940 (2013).
|
|
"Assembly of a
Three-dimensional Multi-type Bronchiole Co-culture Model Using Magnetic Levitation," H.
Tseng, J. A. Gage, R. M. Raphael, R. H. Moore, T.C. Killian, K. J. Grande-Allen, and G. R. Souza,
Tissue Eng. Part C: Methods
19, 665 (2013).
|
|
"A Microfabricated
Magnetic Force Transducer-Microaspiration System for Studying Membrane Mechanics," D.J.
Stark, T.C. Killian, and R. M. Raphael, Phys. Biol.
8, 056008 (2011).
|
|
"Three-dimensional Tissue Culture
Based on Magnetic Cell Levitation," G. R. Souza, J. R Molina, R. M. Raphael, M. G. Ozawa, D.
J. Stark, C. S. Levin, L. F. Bonk, J. S. Ananta, J. Mandelin,M.M. Georgescu, J. A. Bankson, J. G.
Gelovani, T. C. Killian, R. Pasqualini, and W. Arap, Nature Nanotech. 5, 291 (2010).
|
|
"High-throughput non-viral gene transfer by mRNA electroporation to generate CD19-specific
T cells," Yoonsu Choi, Carrie Yuen, Hillary Gibbons, Sourindra Maiti, Helen Huls, Sibani L
Biswal, Robert Raphael, Thomas C Killian, Daniel J Stark, Dean A Lee, Partow Kebriaei, Richard E
Champlin, and Laurence JN Cooper, Biology of Blood and Marrow Transplantation 15, 22 (2009).
|
Theses
Undergraduate Theses
|
